Alternative Names:

ATG6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; Beclin 1 autophagy related;Beclin-1;Beclin1; BECN1; Protein GT197; VPS30;

Application:

WB IHC ICC/IF IP

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:20

	Western blot analysis of Beclin 1 expression in (1) HEK293 cell lysate; (2) NIH/3T3 cell lysate; (3) C6 cell lysate.
	Immunohistochemical analysis of paraffin-embedded human breast cancer, using Beclin 1 Antibody.
	Immunofluorescent analysis of Hela cells, using Beclin 1 Antibody.

Purification:

Affinity-chromatography

Specificity:

Beclin 1 Antibody detects endogenous levels of total Beclin 1

Immunogen:

A synthesized peptide derived from human Beclin 1

Description:

Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.